Jaakko Tuomilehto Selected Research

Insulin Resistance

12/2023	Fibroblast Growth Factor 21: A More Effective Biomarker Than Free Fatty Acids and Other Insulin Sensitivity Measures for Predicting Non-alcoholic Fatty Liver Disease in Saudi Arabian Type 2 Diabetes Patients.
1/2023	Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake.
1/2022	Measures of Insulin Resistance as a Screening Tool for Dysglycemia in Patients With Coronary Artery Disease: A Report From the EUROASPIRE V Population.
1/2021	Adipose Tissue Steroid Receptor RNA Activator 1 (SRA1) Expression Is Associated with Obesity, Insulin Resistance, and Inflammation.
1/2020	Early prevention of diabetes microvascular complications in people with hyperglycaemia in Europe. ePREDICE randomized trial. Study protocol, recruitment and selected baseline data.
1/2020	Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus with Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia.
1/2020	Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population.
1/2019	A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations.
1/2019	Higher Levels of ANGPTL5 in the Circulation of Subjects With Obesity and Type 2 Diabetes Are Associated With Insulin Resistance.
1/2019	Adipose tissue expression of CCL19 chemokine is positively associated with insulin resistance.

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Jaakko Tuomilehto Research Topics

Disease

122	Type 2 Diabetes Mellitus (MODY) 03/2024 - 01/2002
43	Insulin Resistance 12/2023 - 02/2002
36	Hypertension (High Blood Pressure) 04/2024 - 01/2002
36	Obesity 12/2022 - 04/2004
36	Glucose Intolerance 01/2022 - 07/2003
31	Cardiovascular Diseases (Cardiovascular Disease) 11/2023 - 02/2002
25	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 12/2002
24	Stroke (Strokes) 01/2024 - 06/2002
22	Inflammation (Inflammations) 12/2023 - 04/2010
18	Coronary Disease (Coronary Heart Disease) 10/2023 - 12/2002
17	Dementia (Dementias) 01/2024 - 10/2002
16	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2023 - 05/2002
15	Prediabetic State (Prediabetes) 03/2023 - 09/2009
12	Overweight 01/2022 - 12/2002
11	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022 - 02/2008
10	Hyperglycemia 01/2022 - 01/2005
9	Ischemic Stroke 01/2024 - 09/2005
9	Body Weight (Weight, Body) 03/2023 - 12/2003
9	Dyslipidemias (Dyslipidemia) 01/2021 - 12/2002
8	Diabetes Mellitus 01/2024 - 01/2002
8	Cognitive Dysfunction 01/2024 - 09/2004
8	Weight Loss (Weight Reduction) 12/2022 - 01/2013
8	Myocardial Infarction 02/2013 - 01/2004
7	Abdominal Obesity 01/2018 - 06/2005
7	Isolated Systolic Hypertension 04/2012 - 10/2001
5	Hemorrhagic Stroke 01/2024 - 05/2009
5	Non-alcoholic Fatty Liver Disease 12/2023 - 05/2010
5	Diabetic Nephropathies (Diabetic Nephropathy) 10/2023 - 08/2012
5	Fatty Liver 01/2023 - 06/2013
4	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 01/2002
4	Heart Failure 10/2023 - 01/2004
4	Diabetes Complications 01/2023 - 01/2002
4	Chronic Disease (Chronic Diseases) 07/2018 - 07/2002
4	Gestational Diabetes (Gestational Diabetes Mellitus) 02/2016 - 10/2010
4	Neoplasms (Cancer) 12/2014 - 09/2011
4	Heart Valve Diseases (Valvular Heart Disease) 02/2013 - 09/2010
3	Ankylosing Spondylitis 05/2015 - 08/2008
3	Hyperinsulinism (Hyperinsulinemia) 05/2010 - 05/2004
2	Genetic Risk Score 04/2024 - 10/2013

Drug/Important Bio-Agent (IBA)

126	Glucose (Dextrose)FDA LinkGeneric 03/2024 - 05/2002
40	Insulin (Novolin)FDA Link 11/2023 - 12/2002
31	Antihypertensive Agents (Antihypertensives)IBA 07/2020 - 01/2002
28	CholesterolIBA 11/2023 - 01/2002
20	Triglycerides (Triacylglycerol)IBA 01/2023 - 11/2002
18	HDL CholesterolIBA 01/2023 - 05/2004
16	Biomarkers (Surrogate Marker)IBA 12/2023 - 04/2010
15	LipidsIBA 01/2019 - 01/2002
12	Coffee FDA Link 08/2020 - 03/2004
11	LDL CholesterolIBA 01/2022 - 12/2002
8	Acarbose FDA LinkGeneric 10/2021 - 01/2005
8	Proteins (Proteins, Gene)FDA Link 10/2019 - 01/2018
7	Apolipoproteins E (ApoE)IBA 01/2024 - 08/2002
7	Blood Glucose (Blood Sugar)IBA 01/2023 - 04/2004
7	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2022 - 01/2016
6	Liraglutide FDA Link 01/2022 - 02/2015
6	ApolipoproteinsIBA 01/2018 - 08/2002
5	AlbuminsIBA 10/2023 - 06/2014
5	oxidized low density lipoproteinIBA 01/2022 - 12/2002
5	AdiponectinIBA 07/2018 - 01/2011
5	Vitamin D FDA LinkGeneric 01/2017 - 10/2004
5	HDL LipoproteinsIBA 11/2013 - 12/2008
4	Metformin (Glucophage)FDA LinkGeneric 01/2024 - 07/2016
4	Nonesterified Fatty Acids (NEFA)IBA 12/2023 - 01/2018
4	CreatinineIBA 11/2023 - 11/2002
4	Uric Acid (Urate)IBA 11/2023 - 03/2006
4	UrocortinsIBA 01/2022 - 01/2019
4	Messenger RNA (mRNA)IBA 01/2022 - 09/2002
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 04/2004
4	C-Reactive ProteinIBA 01/2021 - 06/2009
4	Hemoglobins (Hemoglobin)IBA 01/2019 - 01/2016
4	TeaIBA 12/2017 - 11/2007
4	25-hydroxyvitamin DIBA 01/2017 - 11/2013
4	Interleukin-6 (Interleukin 6)IBA 11/2009 - 07/2003
4	AntigensIBA 08/2009 - 05/2002
4	Enalapril FDA LinkGeneric 01/2007 - 10/2001
3	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2022 - 08/2008
3	indolepropionic acidIBA 11/2022 - 11/2017
3	NeuropeptidesIBA 01/2022 - 01/2021
3	C-PeptideIBA 01/2022 - 01/2020
3	SodiumIBA 12/2020 - 02/2002
3	EnzymesIBA 09/2020 - 05/2010
3	ORALIT (ORS)IBA 01/2020 - 10/2005
3	GlucosidasesIBA 01/2020 - 07/2014
3	Hormones (Hormone)IBA 10/2019 - 01/2012
3	PalmitatesIBA 01/2019 - 01/2018
3	LDL Lipoproteins (beta Lipoproteins)IBA 01/2019 - 02/2013
3	CytokinesIBA 07/2018 - 07/2003
3	Dietary Fiber FDA Link 01/2018 - 12/2003
3	Lipoproteins (Lipoprotein)IBA 12/2017 - 05/2004
3	HLA-B Antigens (HLA-B)IBA 05/2015 - 08/2009
3	AntibodiesIBA 04/2013 - 08/2002
3	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 04/2012 - 10/2001
3	Indapamide FDA LinkGeneric 04/2009 - 08/2004
3	Rosuvastatin Calcium (Crestor)FDA Link 06/2005 - 12/2002
2	Docosahexaenoic AcidsIBA 01/2024 - 01/2023

Therapy/Procedure

21	Therapeutics 01/2023 - 10/2001
9	Glycemic Control 01/2021 - 01/2015
5	Injections 01/2022 - 02/2015
3	Cognitive Training 03/2022 - 06/2015
3	Diet Therapy (Therapy, Diet) 06/2007 - 01/2006